Difference between revisions of "NatA"

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(Expression and regulation)
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* '''Description:''' Na+ ABC transporter (export) (ATP-binding protein) <br/><br/>
+
* '''Description:''' Na+ [[ABC transporter]] (export) (ATP-binding protein) <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || Na+ ABC transporter (export) (ATP-binding protein)
+
|style="background:#ABCDEF;" align="center"| '''Product''' || Na+ [[ABC transporter]] (export) (ATP-binding protein)
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Function''' || sodium export
 
|style="background:#ABCDEF;" align="center"|'''Function''' || sodium export
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* '''Catalyzed reaction/ biological activity:'''  
 
* '''Catalyzed reaction/ biological activity:'''  
  
* '''Protein family:''' ABC transporter domain (according to Swiss-Prot)
+
* '''Protein family:''' [[ABC transporter]] domain (according to Swiss-Prot)
  
 
* '''Paralogous protein(s):'''
 
* '''Paralogous protein(s):'''
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* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
  
* '''Interactions:'''
+
* '''Interactions:''' [[NatA]]-[[NatB]] {{PubMed|10092453}}
  
 
* '''Localization:'''
 
* '''Localization:'''

Revision as of 20:25, 13 January 2010

Gene name natA
Synonyms
Essential no
Product Na+ ABC transporter (export) (ATP-binding protein)
Function sodium export
MW, pI 27 kDa, 8.799
Gene length, protein length 738 bp, 246 aa
Immediate neighbours natR, natB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
NatA context.gif
This image was kindly provided by SubtiList




The gene

Basic information

  • Locus tag: BSU02750

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism: NatR: transcription activation PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Mitsuo Ogura, Kensuke Tsukahara, Kentaro Hayashi, Teruo Tanaka
The Bacillus subtilis NatK-NatR two-component system regulates expression of the natAB operon encoding an ABC transporter for sodium ion extrusion.
Microbiology (Reading): 2007, 153(Pt 3);667-675
[PubMed:17322186] [WorldCat.org] [DOI] (P p)

Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453] [WorldCat.org] [DOI] (P p)

J Cheng, A A Guffanti, T A Krulwich
A two-gene ABC-type transport system that extrudes Na+ in Bacillus subtilis is induced by ethanol or protonophore.
Mol Microbiol: 1997, 23(6);1107-20
[PubMed:9106203] [WorldCat.org] [DOI] (P p)