Difference between revisions of "NasC"

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* '''Locus tag:''' BSU03310
 
* '''Locus tag:''' BSU03310
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[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=nasC_358303_360435_-1 Expression]
  
 
===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===

Revision as of 13:29, 24 January 2012

  • Description: nitrate reductase (catalytic subunit)

Gene name nasC
Synonyms narB, nasBB
Essential no
Product nitrate reductase (catalytic subunit)
Function utilization of nitrate
Interactions involving this protein in SubtInteract: NasC
Metabolic function and regulation of this protein in SubtiPathways:
Alternative nitrogen sources
MW, pI 78 kDa, 6.728
Gene length, protein length 2130 bp, 710 aa
Immediate neighbours nasD, nasB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
NasC context.gif
This image was kindly provided by SubtiList





Categories containing this gene/protein

utilization of nitrogen sources other than amino acids

This gene is a member of the following regulons

TnrA regulon

The gene

Basic information

  • Locus tag: BSU03310

Expression

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Nitrite + acceptor = nitrate + reduced acceptor (according to Swiss-Prot)
  • Protein family: prokaryotic molybdopterin-containing oxidoreductase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed in the absence of good nitrogen sources (glutamine or ammonium) (TnrA) PubMed
    • induced by nitric oxide under anaerobic conditions (NsrR) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Víctor M Luque-Almagro, Andrew J Gates, Conrado Moreno-Vivián, Stuart J Ferguson, David J Richardson, M Dolores Roldán
Bacterial nitrate assimilation: gene distribution and regulation.
Biochem Soc Trans: 2011, 39(6);1838-43
[PubMed:22103536] [WorldCat.org] [DOI] (I p)

Original publications