Difference between revisions of "NarK"

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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[fnr]]'', ''[[argS]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[fnr]]'', ''[[argS]]''
 
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU37320 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU37320 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU37320 Advanced_DNA]
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU37320 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU37320 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU37320 DNA_with_flanks]
 
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Revision as of 11:32, 14 May 2013

  • Description: nitrite extrusion protein

Gene name narK
Synonyms
Essential no
Product nitrite extrusion protein
Function nitrate respiration, nitrite export
Gene expression levels in SubtiExpress: narK
Metabolic function and regulation of this protein in SubtiPathways:
Alternative nitrogen sources
MW, pI 42 kDa, 10.099
Gene length, protein length 1185 bp, 395 aa
Immediate neighbours fnr, argS
Sequences Protein DNA DNA_with_flanks
Genetic context
NarK context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
NarK expression.png


























Categories containing this gene/protein

transporters/ other, respiration, membrane proteins

This gene is a member of the following regulons

Fnr regulon, NsrR regulon

The gene

Basic information

  • Locus tag: BSU37320

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s): NasA

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed under anaerobic conditions (Fnr) PubMed
    • induced by nitric oxide under anaerobic conditions (NsrR) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Hannes Hahne, Susanne Wolff, Michael Hecker, Dörte Becher
From complementarity to comprehensiveness--targeting the membrane proteome of growing Bacillus subtilis by divergent approaches.
Proteomics: 2008, 8(19);4123-36
[PubMed:18763711] [WorldCat.org] [DOI] (I p)

Michiko M Nakano, Hao Geng, Shunji Nakano, Kazuo Kobayashi
The nitric oxide-responsive regulator NsrR controls ResDE-dependent gene expression.
J Bacteriol: 2006, 188(16);5878-87
[PubMed:16885456] [WorldCat.org] [DOI] (P p)

Heike Reents, Richard Münch, Thorben Dammeyer, Dieter Jahn, Elisabeth Härtig
The Fnr regulon of Bacillus subtilis.
J Bacteriol: 2006, 188(3);1103-12
[PubMed:16428414] [WorldCat.org] [DOI] (P p)

H Cruz Ramos, L Boursier, I Moszer, F Kunst, A Danchin, P Glaser
Anaerobic transcription activation in Bacillus subtilis: identification of distinct FNR-dependent and -independent regulatory mechanisms.
EMBO J: 1995, 14(23);5984-94
[PubMed:8846791] [WorldCat.org] [DOI] (P p)