nadR

168

transcriptional repressor of genes involved in NAD biosynthesis

locus: BSU_27890

Molecular weight: 19.58 kDa

pI: 5.76

Protein length: 180 aa

Gene length: 543 bp

function: regulation of NAD biosynthesis

product: transcriptional repressor

essential: no

synonyms: nadR, yrxA

List of homologs in different organisms, belongs to COG1827 (Galperin et al., 2021)

Gene

Coordinates: 2,850,716  2,851,258

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The protein

Structure

• [PDB|1J5Y] (from Thermotoga maritima, 38% identity) [pubmed|17256761]
• [AF|P39667]

Biological materials

Mutant

• MGNA-A824 (yrxA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/824 NBRP B. subtilis, Japan]
• BKE27890 ([gene|510DE075EA964D22C42DEB171509F6CDA600A402|nadR]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE27890 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_TTCCTTCAGCCACAGAAGAA,  downstream forward: _UP4_TAAAAAAAGCCCTCTAGTGG
• BKK27890 ([gene|510DE075EA964D22C42DEB171509F6CDA600A402|nadR]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK27890 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_TTCCTTCAGCCACAGAAGAA,  downstream forward: _UP4_TAAAAAAAGCCCTCTAGTGG

labs

• [wiki|Alessandra Albertini], University of Pavia, Italy [http://www-1.unipv.it/genbiom/albertini.html homepage]

References

• 18276644,8444804,16199587,17256761