Difference between revisions of "MurC"

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|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1296 bp, 432 aa  
 
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1296 bp, 432 aa  
 
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|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ytxG]]'', ''[[ytpT]]''
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ytxG]]'', ''[[sftA]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB14957&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
 
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB14957&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''

Revision as of 12:57, 1 October 2009

  • Description: UDP-N-acetylmuramoyl-L-alanine synthetase

Gene name murC
Synonyms ytxF
Essential yes PubMed
Product UDP-N-acetylmuramoyl-L-alanine synthetase
Function peptidoglycan precursor biosynthesis
Metabolic function and regulation of this protein in SubtiPathways:
Cell wall
MW, pI 48 kDa, 5.307
Gene length, protein length 1296 bp, 432 aa
Immediate neighbours ytxG, sftA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
MurC context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU29790

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: ATP + UDP-N-acetylmuramate + L-alanine = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanine (according to Swiss-Prot)
  • Protein family: murCDEF family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot), Cytoplasm (Homogeneous) PubMed

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References