Difference between revisions of "MtnX"
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase | + | |style="background:#ABCDEF;" align="center"| '''Product''' || 2-hydroxy-3-keto-5-methylthiopentenyl-<br/>1-phosphate phosphatase |
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || methionine salvage | |style="background:#ABCDEF;" align="center"|'''Function''' || methionine salvage | ||
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__TOC__ | __TOC__ | ||
| − | <br/><br/> | + | <br/><br/><br/><br/><br/> |
=The gene= | =The gene= | ||
Revision as of 15:55, 16 June 2009
- Description: 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase
| Gene name | mtnX |
| Synonyms | ykrX |
| Essential | no |
| Product | 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate phosphatase |
| Function | methionine salvage |
| MW, pI | 26 kDa, 4.658 |
| Gene length, protein length | 705 bp, 235 aa |
| Immediate neighbours | mtnW, mtnB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU13600
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate (according to Swiss-Prot)
- Protein family: MtnX family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure: 2FEA
- Swiss prot entry: O31667
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulatory mechanism: S-box: transcription termination/ antitermination, the S-box riboswitch binds S-adenosylmethionine resulting in termination PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Ulrike Mäder, Georg Homuth, Christian Scharf, Knut Büttner, Rüdiger Bode, Michael Hecker
Transcriptome and proteome analysis of Bacillus subtilis gene expression modulated by amino acid availability.
J Bacteriol: 2002, 184(15);4288-95
[PubMed:12107147]
[WorldCat.org]
[DOI]
(P p)
Agnieszka Sekowska, Antoine Danchin
The methionine salvage pathway in Bacillus subtilis.
BMC Microbiol: 2002, 2;8
[PubMed:12022921]
[WorldCat.org]
[DOI]
(I e)
Brooke A Murphy, Frank J Grundy, Tina M Henkin
Prediction of gene function in methylthioadenosine recycling from regulatory signals.
J Bacteriol: 2002, 184(8);2314-8
[PubMed:11914366]
[WorldCat.org]
[DOI]
(P p)
