MtnW

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  • Description: 2,3-diketo-5-methylthiopentyl-1-phosphate enolase, Rubisco-like protein <br/><br/>
Gene name mtnW
Synonyms ykrW
Essential no
Product 2,3-diketo-5-methylthiopentyl-1-phosphate enolase
Function methionine salvage
Metabolic function and regulation of this protein in SubtiPathways: <br/>Cys, Met & Sulfate assimilation
MW, pI 44 kDa, 5.284
Gene length, protein length 1242 bp, 414 aa
Immediate neighbours mtnE, mtnX
Get the DNA and protein sequences <br/> (Barbe et al., 2009)
Genetic context <br/> YkrW context.gif
<div align="right"> <small>This image was kindly provided by SubtiList</small></div>

<br/><br/><br/><br/><br/><br/>

The gene

Basic information

  • Locus tag: BSU13590

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 5-(methylthio)-2,3-dioxopentyl phosphate = 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate (according to Swiss-Prot)
  • Protein family: Type IV subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism: S-box: transcription termination/ antitermination, the S-box riboswitch binds S-adenosylmethionine resulting in termination PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

<pubmed>10094622,19279009,12022921,14551435,11914366,, 12107147, 19194007 15102328 19690372 12787499 18039762 </pubmed>