MstX

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  • Description: membrane-integrating protein for membrane protein expression, MISTIC

Gene name mstX
Synonyms
Essential no
Product MISTIC
Function unknown
Gene expression levels in SubtiExpress: mstX
MW, pI 13 kDa, 4.549
Gene length, protein length 330 bp, 110 aa
Immediate neighbours yuzI, yugO
Gene sequence (+200bp) Protein sequence
Genetic context
File:MstX context.gif



Categories containing this gene/protein

protein secretion, biofilm formation, membrane proteins

This gene is a member of the following regulons

SinR regulon

The gene

Basic information

  • Locus tag: BSU31321

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: no entry

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:
    • integral membrane protein that folds autonomously into the membrane, bypassing the cellular translocon machinery PubMed

Database entries

  • KEGG entry: [1]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Matthew E Lundberg, Eric C Becker, Senyon Choe
MstX and a putative potassium channel facilitate biofilm formation in Bacillus subtilis.
PLoS One: 2013, 8(5);e60993
[PubMed:23737939] [WorldCat.org] [DOI] (I e)

Dilip K Debnath, Rajiv Vaid Basaiawmoit, Kåre Lehmann Nielsen, Daniel E Otzen
The role of membrane properties in Mistic folding and dimerisation.
Protein Eng Des Sel: 2011, 24(1-2);89-97
[PubMed:21097953] [WorldCat.org] [DOI] (I p)

Hay Dvir, Matthew E Lundberg, Samir K Maji, Roland Riek, Senyon Choe
Mistic: cellular localization, solution behavior, polymerization, and fibril formation.
Protein Sci: 2009, 18(7);1564-70
[PubMed:19475664] [WorldCat.org] [DOI] (I p)

Tarmo P Roosild, Mark Vega, Samantha Castronovo, Senyon Choe
Characterization of the family of Mistic homologues.
BMC Struct Biol: 2006, 6;10
[PubMed:16704729] [WorldCat.org] [DOI] (I e)

Tarmo P Roosild, Jason Greenwald, Mark Vega, Samantha Castronovo, Roland Riek, Senyon Choe
NMR structure of Mistic, a membrane-integrating protein for membrane protein expression.
Science: 2005, 307(5713);1317-21
[PubMed:15731457] [WorldCat.org] [DOI] (I p)