Difference between revisions of "MsrB"

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=== Basic information ===
 
=== Basic information ===
  
* '''Locus tag:'''
+
* '''Locus tag:''' BSU21680
  
 
===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
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* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P54155 P54155]
 
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P54155 P54155]
  
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU21680 BSU21680]
+
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU21680]
  
 
* '''E.C. number:''' [http://www.expasy.org/enzyme/1.8.4.12 1.8.4.12]
 
* '''E.C. number:''' [http://www.expasy.org/enzyme/1.8.4.12 1.8.4.12]

Revision as of 11:50, 3 June 2009

  • Description: peptide methionine sulfoxide reductase

Gene name msrB
Synonyms yppQ
Essential
Product peptide methionine sulfoxide reductase
Function regeneration of methionine and
restoration of protein function after oxidative damage
MW, pI 16 kDa, 5.842
Gene length, protein length 429 bp, 143 aa
Immediate neighbours ypqP, msrA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YppQ context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU21680

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (R)-S-oxide + thioredoxin (according to Swiss-Prot)
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • KEGG entry: [3]

Additional information

Expression and regulation

Operon: msrA-msrB PubMed

  • Regulation: induced by oxidative stress (Spx)
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed