Difference between revisions of "MscL"

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(Labs working on this gene/protein)
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[[Jan Maarten van Dijl]], Groningen, Netherlands
 
[[Jan Maarten van Dijl]], Groningen, Netherlands
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[[Erhard Bremer]], University of Marburg, Germany [http://www.uni-marburg.de/fb17/fachgebiete/mikrobio/molmibi homepage]
  
 
=Your additional remarks=
 
=Your additional remarks=

Revision as of 18:05, 7 April 2009

  • Description: large conductance mechanosensitive channel protein, prevents selective release of cytoplasmic proteins in a hypotonic environment

Gene name mscL
Synonyms ywpC
Essential no
Product large conductance mechanosensitive channel protein
Function resistance to osmotic downshockglycine betaine export
MW, pI 14 kDa, 4.649
Gene length, protein length 390 bp, 130 aa
Immediate neighbours ywpD, ywpB
Gene sequence (+200bp) Protein sequence
Genetic context
MscL context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

sensitive to osmotic downshock (> 0.5 M) during logarithmic growth PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: membrane PubMed

Database entries

  • Structure:
  • Swiss prot entry:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation: expressed in logarithmic phase PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Jan Maarten van Dijl, Groningen, Netherlands

Erhard Bremer, University of Marburg, Germany homepage

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed