Difference between revisions of "Mpr"

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|style="background:#ABCDEF;" align="center"|'''Function''' || protein degradation  
 
|style="background:#ABCDEF;" align="center"|'''Function''' || protein degradation  
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU02240 mpr]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU02240 mpr]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 33 kDa, 8.967   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 33 kDa, 8.967   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[purT]]'', ''[[ybfJ]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[purT]]'', ''[[ybfJ]]''
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB12018&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU02240 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU02240 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU02240 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:mpr_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:mpr_context.gif]]

Revision as of 12:02, 13 May 2013

  • Description: extracellular metalloprotease

Gene name mpr
Synonyms
Essential no
Product extracellular metalloprotease
Function protein degradation
Gene expression levels in SubtiExpress: mpr
MW, pI 33 kDa, 8.967
Gene length, protein length 939 bp, 313 aa
Immediate neighbours purT, ybfJ
Sequences Protein DNA Advanced_DNA
Genetic context
Mpr context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
Mpr expression.png















Categories containing this gene/protein

utilization of nitrogen sources other than amino acids, proteolysis

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU02240

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: peptidase S1B family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation: repressed by casamino acids PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Massimiliano Marvasi, Pieter T Visscher, Lilliam Casillas Martinez
Exopolymeric substances (EPS) from Bacillus subtilis: polymers and genes encoding their synthesis.
FEMS Microbiol Lett: 2010, 313(1);1-9
[PubMed:20735481] [WorldCat.org] [DOI] (I p)

Original publications

Birgit Voigt, Haike Antelmann, Dirk Albrecht, Armin Ehrenreich, Karl-Heinz Maurer, Stefan Evers, Gerhard Gottschalk, Jan Maarten van Dijl, Thomas Schweder, Michael Hecker
Cell physiology and protein secretion of Bacillus licheniformis compared to Bacillus subtilis.
J Mol Microbiol Biotechnol: 2009, 16(1-2);53-68
[PubMed:18957862] [WorldCat.org] [DOI] (I p)

Chi Hye Park, Sang Jun Lee, Sung Gu Lee, Weon Sup Lee, Si Myung Byun
Hetero- and autoprocessing of the extracellular metalloprotease (Mpr) in Bacillus subtilis.
J Bacteriol: 2004, 186(19);6457-64
[PubMed:15375126] [WorldCat.org] [DOI] (P p)

Ulrike Mäder, Georg Homuth, Christian Scharf, Knut Büttner, Rüdiger Bode, Michael Hecker
Transcriptome and proteome analysis of Bacillus subtilis gene expression modulated by amino acid availability.
J Bacteriol: 2002, 184(15);4288-95
[PubMed:12107147] [WorldCat.org] [DOI] (P p)