MoaA
- Description: molybdopterin precursor biosynthesis
| Gene name | moaA |
| Synonyms | narA, narAB |
| Essential | no |
| Product | unknown |
| Function | nitrate respiration |
| Gene expression levels in SubtiExpress: moaA | |
| MW, pI | 38 kDa, 9.285 |
| Gene length, protein length | 1023 bp, 341 aa |
| Immediate neighbours | rapB, fdhD |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU36700
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- involved in the first step of molybdenum cofactor biosynthesis (together with YdiG)
- Protein family: MoaA family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- Cofactors: contains an iron-sulfur cluster
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P39757
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: moaA PubMed
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Ralf R Mendel
The molybdenum cofactor.
J Biol Chem: 2013, 288(19);13165-72
[PubMed:23539623]
[WorldCat.org]
[DOI]
(I p)
Original publications
M M Nakano, Y P Dailly, P Zuber, D P Clark
Characterization of anaerobic fermentative growth of Bacillus subtilis: identification of fermentation end products and genes required for growth.
J Bacteriol: 1997, 179(21);6749-55
[PubMed:9352926]
[WorldCat.org]
[DOI]
(P p)
P Glaser, A Danchin, F Kunst, P Zuber, M M Nakano
Identification and isolation of a gene required for nitrate assimilation and anaerobic growth of Bacillus subtilis.
J Bacteriol: 1995, 177(4);1112-5
[PubMed:7860592]
[WorldCat.org]
[DOI]
(P p)
