Difference between revisions of "MmgB"

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=The gene=
 
=The gene=

Revision as of 15:08, 22 June 2009

  • Description: 3-hydroxyacyl-CoA dehydrogenase (acetoacetyl-CoA)

Gene name mmgB
Synonyms yqiM
Essential no
Product 3-hydroxyacyl-CoA dehydrogenase (acetoacetyl-CoA)
Function mother cell metabolism
Metabolic function and regulation of this protein in SubtiPathways:
Central C-metabolism
MW, pI 26 kDa, 6.602
Gene length, protein length 732 bp, 244 aa
Immediate neighbours mmgC, mmgA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
MmgB context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU24160

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: (S)-3-hydroxybutanoyl-CoA + NADP+ = 3-acetoacetyl-CoA + NADPH (according to Swiss-Prot)
  • Protein family: 3-hydroxyacyl-CoA dehydrogenase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Operon:
  • Regulation: repressed by glucose (CcpA)
  • Regulatory mechanism: CcpA: transcription repression
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

E M Bryan, B W Beall, C P Moran
A sigma E dependent operon subject to catabolite repression during sporulation in Bacillus subtilis.
J Bacteriol: 1996, 178(16);4778-86
[PubMed:8759838] [WorldCat.org] [DOI] (P p)