Difference between revisions of "MinC"
| Line 37: | Line 37: | ||
= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
| − | {{SubtiWiki regulon|[[SigH regulon]]}} | + | {{SubtiWiki regulon|[[SigH regulon]]}}, |
| + | {{SubtiWiki regulon|[[SigM regulon]]}} | ||
=The gene= | =The gene= | ||
| Line 100: | Line 101: | ||
=Expression and regulation= | =Expression and regulation= | ||
* '''Operon:''' | * '''Operon:''' | ||
| + | ** ''[[radC]]-[[mreB]]-[[mreC]]-[[mreD]]-[[minC]]-[[minD]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/18179421 PubMed] | ||
** ''[[mreB]]-[[mreC]]-[[mreD]]-[[minC]]-[[minD]]'' {{PubMed|8459776}} | ** ''[[mreB]]-[[mreC]]-[[mreD]]-[[minC]]-[[minD]]'' {{PubMed|8459776}} | ||
** ''[[minC]]-[[minD]]'' {{PubMed|8459776}} | ** ''[[minC]]-[[minD]]'' {{PubMed|8459776}} | ||
* '''[[Sigma factor]]:''' | * '''[[Sigma factor]]:''' | ||
| + | ** ''[[radC]]'': [[SigM]] {{PubMed|18179421}} | ||
| + | ** ''[[mreB]]'': [[SigH]] [http://www.ncbi.nlm.nih.gov/sites/entrez/8459776 PubMed] | ||
** ''[[minC]]'': [[SigH]] {{PubMed|8459776}} | ** ''[[minC]]'': [[SigH]] {{PubMed|8459776}} | ||
Revision as of 15:56, 17 May 2011
- Description: cell-division inhibitor (septum placement), destabilizes FtsZ-rings at new cell poles
| Gene name | minC |
| Synonyms | |
| Essential | no |
| Product | cell-division inhibitor |
| Function | septum placement |
| MW, pI | 24 kDa, 6.262 |
| Gene length, protein length | 678 bp, 226 aa |
| Immediate neighbours | minD, mreD |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
cell division, cell envelope stress proteins (controlled by SigM, W, X, Y), membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU28000
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: The Min system prevents minicell formation adjacent to recently completed division sites by promoting the disassembly of the cytokinetic ring, thereby ensuring that cell division occurs only once per cell cycle PubMed
- Protein family: minC family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- Structure:
- UniProt: Q01463
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Marc Bramkamp, Suey van Baarle
Division site selection in rod-shaped bacteria.
Curr Opin Microbiol: 2009, 12(6);683-8
[PubMed:19884039]
[WorldCat.org]
[DOI]
(I p)
David W Adams, Jeff Errington
Bacterial cell division: assembly, maintenance and disassembly of the Z ring.
Nat Rev Microbiol: 2009, 7(9);642-53
[PubMed:19680248]
[WorldCat.org]
[DOI]
(I p)
Original Publications
