Difference between revisions of "MhqR"

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|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of resistance to quinones and diamide
 
|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of resistance to quinones and diamide
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU13670 mhqR]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU13670 mhqR]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 16 kDa, 6.42   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 16 kDa, 6.42   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[kinD]]'', ''[[motB]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[kinD]]'', ''[[motB]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB13240&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU13670 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU13670 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU13670 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:ykvE_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:ykvE_context.gif]]

Revision as of 12:40, 13 May 2013

Gene name mhqR
Synonyms ykvE
Essential no
Product MarR-family transcriptional repressor
Function regulation of resistance to quinones and diamide
Gene expression levels in SubtiExpress: mhqR
MW, pI 16 kDa, 6.42
Gene length, protein length 435 bp, 145 aa
Immediate neighbours kinD, motB
Sequences Protein DNA Advanced_DNA
Genetic context
YkvE context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
MhqR expression.png
























Categories containing this gene/protein

transcription factors and their control, resistance against oxidative and electrophile stress

This gene is a member of the following regulons

The MhqR regulon

The gene

Basic information

  • Locus tag: BSU13670

Phenotypes of a mutant

  • resistant to quinones and diamide

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

  • Binding site: tATCTcgaAtTCgAGATaaaa PubMed

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Haike Antelmann,University of Greifswald, Germany

Your additional remarks

References

Reviews

Haike Antelmann, Michael Hecker, Peter Zuber
Proteomic signatures uncover thiol-specific electrophile resistance mechanisms in Bacillus subtilis.
Expert Rev Proteomics: 2008, 5(1);77-90
[PubMed:18282125] [WorldCat.org] [DOI] (I p)


Original articles