Difference between revisions of "MhqR"

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* '''Description:''' MarR-family transcriptional repressor of '''[azoR2]''','''[mhqA]''','''[mhqD]''','''[mhqE]''','''[mhqN]''','''[mhqO]''','''[mhqP]''' expression <br/><br/>
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* '''Description:''' MarR-family transcriptional repressor of azoR2, mhqA, mhqDE and mhqNOP expression <br/><br/>
  
 
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=The [[MhqR regulon]]=
 
=The [[MhqR regulon]]=
  
* '''[azoR2]''','''[mhqA]''','''[mhqD]''','''[mhqE]''','''[mhqN]''','''[mhqO]''','''[mhqP]'''
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* azoR2, mhqA, mhqDE and mhqNOP
  
 
=The gene=
 
=The gene=

Revision as of 15:57, 15 December 2011

  • Description: MarR-family transcriptional repressor of azoR2, mhqA, mhqDE and mhqNOP expression

Gene name mhqR
Synonyms ykvE
Essential no
Product MarR-family transcriptional repressor
Function regulation of resistance to quinones and diamide
MW, pI 16 kDa, 6.42
Gene length, protein length 435 bp, 145 aa
Immediate neighbours kinD, motB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YkvE context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

transcription factors and their control, resistance against oxidative and electrophile stress

This gene is a member of the following regulons

The MhqR regulon

  • azoR2, mhqA, mhqDE and mhqNOP

The gene

Basic information

  • Locus tag: BSU13670

Phenotypes of a mutant

  • resistant to quinones and diamide

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

  • Binding site: tATCTcgaAtTCgAGATaaaa PubMed

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Stefanie Töwe, Montira Leelakriangsak, Kazuo Kobayashi, Nguyen Van Duy, Michael Hecker, Peter Zuber, Haike Antelmann
The MarR-type repressor MhqR (YkvE) regulates multiple dioxygenases/glyoxalases and an azoreductase which confer resistance to 2-methylhydroquinone and catechol in Bacillus subtilis.
Mol Microbiol: 2007, 66(1);40-54
[PubMed:17725564] [WorldCat.org] [DOI] (P p)