Difference between revisions of "MhqP"

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* '''Operon:'''  
 
* '''Operon:'''  
 +
** ''[[mhqN]]-[[mhqO]]-[[mhqP]]'' {{PubMed|17725564}}
 +
** ''[[mhqO]]-[[mhqP]]'' {{PubMed|11532142}}
  
* '''[[[[Sigma factor]]]]:'''  
+
* '''[[Sigma factor]]:'''
 +
** ''[[mhqN]]'': [[SigA]] {{PubMed|17725564}}
 +
** ''[[mhqO]]'': [[SigB]] {{PubMed|11532142}}
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
 +
** induced by catechol and 2-methylhydroquinone ([[MhqR]]) {{PubMed|17725564}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 +
** [[MhqR]]: transcription repression {{PubMed|17725564}}
  
* '''Additional information:'''  
+
* '''Additional information:'''
  
 
=Biological materials =
 
=Biological materials =
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=References=
 
=References=
  
<pubmed>17407181,17725564,, </pubmed>
+
<pubmed>17407181,17725564,11532142, </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 20:50, 22 August 2009

  • Description: may be involved in protection against methyl-hydroquinone

Gene name mhqP
Synonyms ydfP
Essential no
Product unknown
Function may be involved in protection against methyl-hydroquinone
MW, pI 13 kDa, 8.62
Gene length, protein length 387 bp, 129 aa
Immediate neighbours mhqO, ydfQ
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YdfP context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU05500

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • induced by catechol and 2-methylhydroquinone (MhqR) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Stefanie Töwe, Montira Leelakriangsak, Kazuo Kobayashi, Nguyen Van Duy, Michael Hecker, Peter Zuber, Haike Antelmann
The MarR-type repressor MhqR (YkvE) regulates multiple dioxygenases/glyoxalases and an azoreductase which confer resistance to 2-methylhydroquinone and catechol in Bacillus subtilis.
Mol Microbiol: 2007, 66(1);40-54
[PubMed:17725564] [WorldCat.org] [DOI] (P p)

Van Duy Nguyen, Carmen Wolf, Ulrike Mäder, Michael Lalk, Peter Langer, Ulrike Lindequist, Michael Hecker, Haike Antelmann
Transcriptome and proteome analyses in response to 2-methylhydroquinone and 6-brom-2-vinyl-chroman-4-on reveal different degradation systems involved in the catabolism of aromatic compounds in Bacillus subtilis.
Proteomics: 2007, 7(9);1391-408
[PubMed:17407181] [WorldCat.org] [DOI] (P p)

C W Price, P Fawcett, H Cérémonie, N Su, C K Murphy, P Youngman
Genome-wide analysis of the general stress response in Bacillus subtilis.
Mol Microbiol: 2001, 41(4);757-74
[PubMed:11532142] [WorldCat.org] [DOI] (P p)