Difference between revisions of "MhqN"

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(Expression and regulation)
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= Categories containing this gene/protein =
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{{SubtiWiki category|[[resistance against oxidative and electrophile stress]]}}
 
=The protein=
 
=The protein=
  

Revision as of 17:59, 30 November 2010

  • Description: similar to NAD(P)H nitroreductase

Gene name mhqN
Synonyms ydfN
Essential no
Product unknown
Function unknown
MW, pI 23 kDa, 5.562
Gene length, protein length 618 bp, 206 aa
Immediate neighbours ydfM, mhqO
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YdfN context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU05480

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

Categories containing this gene/protein

resistance against oxidative and electrophile stress

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: nitroreductase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • induced by catechol and 2-methylhydroquinone (MhqR) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Stefanie Töwe, Montira Leelakriangsak, Kazuo Kobayashi, Nguyen Van Duy, Michael Hecker, Peter Zuber, Haike Antelmann
The MarR-type repressor MhqR (YkvE) regulates multiple dioxygenases/glyoxalases and an azoreductase which confer resistance to 2-methylhydroquinone and catechol in Bacillus subtilis.
Mol Microbiol: 2007, 66(1);40-54
[PubMed:17725564] [WorldCat.org] [DOI] (P p)

Van Duy Nguyen, Carmen Wolf, Ulrike Mäder, Michael Lalk, Peter Langer, Ulrike Lindequist, Michael Hecker, Haike Antelmann
Transcriptome and proteome analyses in response to 2-methylhydroquinone and 6-brom-2-vinyl-chroman-4-on reveal different degradation systems involved in the catabolism of aromatic compounds in Bacillus subtilis.
Proteomics: 2007, 7(9);1391-408
[PubMed:17407181] [WorldCat.org] [DOI] (P p)