Difference between revisions of "MhqE"

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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[mhqD]]'', ''[[yoyD]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[mhqD]]'', ''[[yoyD]]''
 
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU19570 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU19570 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU19570 Advanced_DNA]
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU19570 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU19570 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU19570 DNA_with_flanks]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:yodE_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:yodE_context.gif]]

Revision as of 10:26, 14 May 2013

  • Description: dioxygenase/glyoxalase

Gene name mhqE
Synonyms yodE
Essential no
Product dioxygenase/glyoxalase
Function resistance to methyl hydroquinone and catechol
Gene expression levels in SubtiExpress: mhqE
MW, pI 33 kDa, 5.041
Gene length, protein length 909 bp, 303 aa
Immediate neighbours mhqD, yoyD
Sequences Protein DNA DNA_with_flanks
Genetic context
YodE context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
MhqE expression.png
























Categories containing this gene/protein

resistance against oxidative and electrophile stress

This gene is a member of the following regulons

MhqR regulon

The gene

Basic information

  • Locus tag: BSU19570

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 3OAJ (MhqO, 48% identical residues)
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Stefanie Töwe, Montira Leelakriangsak, Kazuo Kobayashi, Nguyen Van Duy, Michael Hecker, Peter Zuber, Haike Antelmann
The MarR-type repressor MhqR (YkvE) regulates multiple dioxygenases/glyoxalases and an azoreductase which confer resistance to 2-methylhydroquinone and catechol in Bacillus subtilis.
Mol Microbiol: 2007, 66(1);40-54
[PubMed:17725564] [WorldCat.org] [DOI] (P p)

Van Duy Nguyen, Carmen Wolf, Ulrike Mäder, Michael Lalk, Peter Langer, Ulrike Lindequist, Michael Hecker, Haike Antelmann
Transcriptome and proteome analyses in response to 2-methylhydroquinone and 6-brom-2-vinyl-chroman-4-on reveal different degradation systems involved in the catabolism of aromatic compounds in Bacillus subtilis.
Proteomics: 2007, 7(9);1391-408
[PubMed:17407181] [WorldCat.org] [DOI] (P p)