Difference between revisions of "MgsR"

From SubtiWiki
Jump to: navigation, search
Line 56: Line 56:
 
* '''Catalyzed reaction/ biological activity:''' exerts a positive or negative effect on the expression of 53 or 18 stress genes, respectively [http://www.ncbi.nlm.nih.gov/sites/entrez/18643936 PubMed]
 
* '''Catalyzed reaction/ biological activity:''' exerts a positive or negative effect on the expression of 53 or 18 stress genes, respectively [http://www.ncbi.nlm.nih.gov/sites/entrez/18643936 PubMed]
  
* '''Protein family:''' Arsenate Reductase (ArsC) family, Spx subfamily
+
* '''Protein family:''' arsC family (according to Swiss-Prot) Arsenate Reductase (ArsC) family, Spx subfamily
  
 
* '''Paralogous protein(s):''' [[Spx]]
 
* '''Paralogous protein(s):''' [[Spx]]

Revision as of 11:29, 21 May 2009

  • Description: transcriptional regulator of a subset of the SigB general stress regulon

Gene name mgsR
Synonyms yqgZ
Essential no
Product transcriptional regulator
Function controls a subset of general stress genes
MW, pI 14 kDa, 9.28
Gene length, protein length 378 bp, 126 aa
Immediate neighbours trnSL-Gln1, yqgY
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YqgZ context.gif
This image was kindly provided by SubtiList





The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: exerts a positive or negative effect on the expression of 53 or 18 stress genes, respectively PubMed
  • Protein family: arsC family (according to Swiss-Prot) Arsenate Reductase (ArsC) family, Spx subfamily
  • Paralogous protein(s): Spx

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation: repressed by casamino acids PubMed , induced by stress (SigB) PubMed, expressed under stress conditions PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Mäder et al. (2002) Transcriptome and Proteome Analysis of Bacillus subtilis Gene Expression Modulated by Amino Acid Availability. J. Bacteriol 184: 1844288-4295 PubMed
  2. Höper et al. (2005) Comprehensive Characterization of the Contribution of Individual SigB-Dependent General Stress Genes to Stress Resistance of Bacillus subtilis. J. Bact. 187: 2810-2826 PubMed
  3. Reder et al. (2008) The Spx paralogue MgsR (YqgZ) controls a subregulon within the general stress response of Bacillus subtilis. Mol. Microbiol. 69: 1104-1120. PubMed
  4. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed