MenA

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  • Description: probable 1,4-dihydroxy-2-naphthoate octaprenyltransferase

Gene name menA
Synonyms ywaB, ipa-6d
Essential yes PubMed
Product probable 1,4-dihydroxy-2-naphthoate octaprenyltransferase
Function biosynthesis of menaquinone
Gene expression levels in SubtiExpress: menA
Metabolic function and regulation of this protein in SubtiPathways:
Menaquinone
MW, pI 33 kDa, 9.32
Gene length, protein length 933 bp, 311 aa
Immediate neighbours ywaC, ywzH
Sequences Protein DNA DNA_with_flanks
Genetic context
MenA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
MenA expression.png




























Categories containing this gene/protein

biosynthesis of cofactors, essential genes, membrane proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU38490

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: menA family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

E Presecan, I Moszer, L Boursier, H Cruz Ramos, V de la Fuente, M-F Hullo, C Lelong, S Schleich, A Sekowska, B H Song, G Villani, F Kunst, A Danchin, P Glaser
The Bacillus subtilis genome from gerBC (311 degrees) to licR (334 degrees).
Microbiology (Reading): 1997, 143 ( Pt 10);3313-3328
[PubMed:9353933] [WorldCat.org] [DOI] (P p)