Difference between revisions of "Mdr"

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(Expression and regulation)
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* '''Operon:'''  
 
* '''Operon:'''  
  
* '''Sigma factor:'''  
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* '''[[Sigma factor]]:'''  
  
 
* '''Regulation:''' expression activated by glucose (3.6 fold) [http://www.ncbi.nlm.nih.gov/pubmed/12850135 PubMed]   
 
* '''Regulation:''' expression activated by glucose (3.6 fold) [http://www.ncbi.nlm.nih.gov/pubmed/12850135 PubMed]   

Revision as of 09:22, 8 April 2009

  • Description: multidrug-efflux transporter (puromycin, nerfloxacin, tosufloxacin)

Gene name mdr
Synonyms ycgD, bmr3
Essential no
Product multidrug-efflux transporter (puromycin, nerfloxacin, tosufloxacin)
Function drug resistance
MW, pI 46 kDa, 9.701
Gene length, protein length 1278 bp, 426 aa
Immediate neighbours lctP, ycgE
Gene sequence (+200bp) Protein sequence
Caution: The sequence for this gene in SubtiList contains errors
Genetic context
Mdr context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • Swiss prot entry:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation: expression activated by glucose (3.6 fold) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Blencke et al. (2003) Transcriptional profiling of gene expression in response to glucose in Bacillus subtilis: regulation of the central metabolic pathways. Metab Eng. 5: 133-149 PubMed
  2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed