Difference between revisions of "Mdr"

From SubtiWiki
Jump to: navigation, search
(Extended information on the protein)
Line 45: Line 45:
  
 
* '''Locus tag:''' BSU03070
 
* '''Locus tag:''' BSU03070
 +
 +
[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=mdr_332441_333979_-1 Expression]
  
 
===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===

Revision as of 13:22, 24 January 2012

  • Description: multidrug-efflux transporter (puromycin, nerfloxacin, tosufloxacin)

Gene name mdr
Synonyms ycgD, bmr3
Essential no
Product multidrug-efflux transporter (puromycin, nerfloxacin, tosufloxacin)
Function drug resistance
MW, pI 46 kDa, 9.701
Gene length, protein length 1278 bp, 426 aa
Immediate neighbours lctP, ycgE
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
Mdr context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

transporters/ other, resistance against toxins/ antibiotics

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU03070

Expression

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation: expression activated by glucose (3.6 fold) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Hans-Matti Blencke, Georg Homuth, Holger Ludwig, Ulrike Mäder, Michael Hecker, Jörg Stülke
Transcriptional profiling of gene expression in response to glucose in Bacillus subtilis: regulation of the central metabolic pathways.
Metab Eng: 2003, 5(2);133-49
[PubMed:12850135] [WorldCat.org] [DOI] (P p)