Difference between revisions of "MalP"

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(Extended information on the protein)
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* '''Localization:''' cell membrane (according to Swiss-Prot)
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** cell membrane (according to Swiss-Prot)
  
 
=== Database entries ===
 
=== Database entries ===

Revision as of 17:51, 25 November 2011

Gene name malP
Synonyms glvC
Essential no
Product maltose-specific phosphotransferase system, EIICB
Function maltose uptake and phosphorylation
Metabolic function and regulation of this protein in SubtiPathways:
Sugar catabolism
MW, pI 57 kDa, 8.872
Gene length, protein length 1581 bp, 527 aa
Immediate neighbours glvR, yfiB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
MalP context.gif
This image was kindly provided by SubtiList







Categories containing this gene/protein

phosphotransferase systems, utilization of specific carbon sources, membrane proteins, phosphoproteins

This gene is a member of the following regulons

CcpA regulon, GlvR regulon

The gene

Basic information

  • Locus tag: BSU08200

Phenotypes of a mutant

no growth on maltose as single carbon source PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Protein EIIB N(pi)-phospho-L-histidine/cysteine + sugar = protein EIIB + sugar phosphate (according to Swiss-Prot)
  • Protein family: PTS permease, glucose permease (Glc) family PubMed
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Additional information:

Biological materials

  • Mutant: GP110 (spc), available in Stülke lab
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Stefan Schönert, Sabine Seitz, Holger Krafft, Eva-Anne Feuerbaum, Iris Andernach, Gabriele Witz, Michael K Dahl
Maltose and maltodextrin utilization by Bacillus subtilis.
J Bacteriol: 2006, 188(11);3911-22
[PubMed:16707683] [WorldCat.org] [DOI] (P p)

H Yamamoto, M Serizawa, J Thompson, J Sekiguchi
Regulation of the glv operon in Bacillus subtilis: YfiA (GlvR) is a positive regulator of the operon that is repressed through CcpA and cre.
J Bacteriol: 2001, 183(17);5110-21
[PubMed:11489864] [WorldCat.org] [DOI] (P p)

Jonathan Reizer, Steffi Bachem, Aiala Reizer, Maryvonne Arnaud, Milton H Saier, Jörg Stülke
Novel phosphotransferase system genes revealed by genome analysis - the complete complement of PTS proteins encoded within the genome of Bacillus subtilis.
Microbiology (Reading): 1999, 145 ( Pt 12);3419-3429
[PubMed:10627040] [WorldCat.org] [DOI] (P p)