MalL

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  • Description: alpha-glucosidase

Gene name malL
Synonyms yvdL
Essential no
Product alpha-glucosidase
Function starch and maltodextrin utilization
Gene expression levels in SubtiExpress: malL
Metabolic function and regulation of this protein in SubtiPathways:
malL
MW, pI 65 kDa, 4.98
Gene length, protein length 1683 bp, 561 aa
Immediate neighbours pgcM, yvdK
Sequences Protein DNA DNA_with_flanks
Genetic context
MalL context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
MalL expression.png




























Categories containing this gene/protein

utilization of specific carbon sources

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU34560

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Hydrolysis of (1->6)-alpha-D-glucosidic linkages in some oligosaccharides produced from starch and glycogen by alpha-amylase, and in isomaltose (according to Swiss-Prot)
  • Protein family: glycosyl hydrolase 13 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 1UOK (from Bacillus cereus, 57% identity, 74% similarity) PubMed
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
    • induced in the presence of maltose PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Stefan Schönert, Sabine Seitz, Holger Krafft, Eva-Anne Feuerbaum, Iris Andernach, Gabriele Witz, Michael K Dahl
Maltose and maltodextrin utilization by Bacillus subtilis.
J Bacteriol: 2006, 188(11);3911-22
[PubMed:16707683] [WorldCat.org] [DOI] (P p)

S Schönert, T Buder, M K Dahl
Properties of maltose-inducible alpha-glucosidase MalL (sucrase-isomaltase-maltase) in Bacillus subtilis: evidence for its contribution to maltodextrin utilization.
Res Microbiol: 1999, 150(3);167-77
[PubMed:10229946] [WorldCat.org] [DOI] (P p)

S Schönert, T Buder, M K Dahl
Identification and enzymatic characterization of the maltose-inducible alpha-glucosidase MalL (sucrase-isomaltase-maltase) of Bacillus subtilis.
J Bacteriol: 1998, 180(9);2574-8
[PubMed:9573215] [WorldCat.org] [DOI] (P p)