Difference between revisions of "MalL"

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|style="background:#ABCDEF;" align="center"|'''Function''' || starch and maltodextrin utilization
 
|style="background:#ABCDEF;" align="center"|'''Function''' || starch and maltodextrin utilization
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU34560 malL]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU34560 malL]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/carbohydrate_metabolic_pathways.html Sugar catabolism], [http://subtiwiki.uni-goettingen.de/pathways/carbohydrate_metabolic_pathways.html Sugar catabolism]'''
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/carbohydrate_metabolic_pathways.html Sugar catabolism], [http://subtiwiki.uni-goettingen.de/pathways/carbohydrate_metabolic_pathways.html Sugar catabolism]'''
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[pgcM]]'', ''[[yvdK]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[pgcM]]'', ''[[yvdK]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB15461&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU34560 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU34560 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU34560 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:malL_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:malL_context.gif]]

Revision as of 13:55, 13 May 2013

  • Description: alpha-glucosidase

Gene name malL
Synonyms yvdL
Essential no
Product alpha-glucosidase
Function starch and maltodextrin utilization
Gene expression levels in SubtiExpress: malL
Metabolic function and regulation of this protein in SubtiPathways:
Sugar catabolism, Sugar catabolism
MW, pI 65 kDa, 4.98
Gene length, protein length 1683 bp, 561 aa
Immediate neighbours pgcM, yvdK
Sequences Protein DNA Advanced_DNA
Genetic context
MalL context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
MalL expression.png




























Categories containing this gene/protein

utilization of specific carbon sources

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU34560

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Hydrolysis of (1->6)-alpha-D-glucosidic linkages in some oligosaccharides produced from starch and glycogen by alpha-amylase, and in isomaltose (according to Swiss-Prot)
  • Protein family: glycosyl hydrolase 13 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 1UOK (from Bacillus cereus, 57% identity, 74% similarity) PubMed
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
    • induced in the presence of maltose PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Stefan Schönert, Sabine Seitz, Holger Krafft, Eva-Anne Feuerbaum, Iris Andernach, Gabriele Witz, Michael K Dahl
Maltose and maltodextrin utilization by Bacillus subtilis.
J Bacteriol: 2006, 188(11);3911-22
[PubMed:16707683] [WorldCat.org] [DOI] (P p)

S Schönert, T Buder, M K Dahl
Properties of maltose-inducible alpha-glucosidase MalL (sucrase-isomaltase-maltase) in Bacillus subtilis: evidence for its contribution to maltodextrin utilization.
Res Microbiol: 1999, 150(3);167-77
[PubMed:10229946] [WorldCat.org] [DOI] (P p)

S Schönert, T Buder, M K Dahl
Identification and enzymatic characterization of the maltose-inducible alpha-glucosidase MalL (sucrase-isomaltase-maltase) of Bacillus subtilis.
J Bacteriol: 1998, 180(9);2574-8
[PubMed:9573215] [WorldCat.org] [DOI] (P p)