Difference between revisions of "Main Page"

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<big>'''Upcoming events:'''</big>  
 
<big>'''Upcoming events:'''</big>  
* The next European BACELL meeting will take place in Bratislava from April 29 to April 30, 2014. The meeting will be organized by [[Imrich Barak]], [http://www.imb.savba.sk/dept/mige/bacell/index.php website], [mailto:Imrich.Barak@savba.sk contact], [[program]]
 
 
* [[PTS meeting 2014|PTS 50 - The PTS celebrates 50 years of transport and regulation]], organized by [[Josef Deutscher]], [[Milton Saier]] and [[Jörg Stülke]] will take place from September 07 to 08 in Göttingen, Germany. [[PTS meeting 2014|website]], [http://subtiwiki.uni-goettingen.de/data/Registration_from_PTS50.doc Registration form], [mailto:jstuelk@gwdg.de contact]
 
* [[PTS meeting 2014|PTS 50 - The PTS celebrates 50 years of transport and regulation]], organized by [[Josef Deutscher]], [[Milton Saier]] and [[Jörg Stülke]] will take place from September 07 to 08 in Göttingen, Germany. [[PTS meeting 2014|website]], [http://subtiwiki.uni-goettingen.de/data/Registration_from_PTS50.doc Registration form], [mailto:jstuelk@gwdg.de contact]
 
* The [[PTM meeting 2014|1st International Conference on Post-Translational Modifications in Bacteria]], organized by [[Ivan Mijakovic]], Christophe Grangeasse, Alan Kent Nielsen and [[Jörg Stülke]] will take place from September 09 to 10 in Göttingen, Germany. [[PTM meeting 2014|website]], [http://subtiwiki.uni-goettingen.de/data/Registration_form_PTM_2014 Registration form], [mailto:jstuelk@gwdg.de contact]
 
* The [[PTM meeting 2014|1st International Conference on Post-Translational Modifications in Bacteria]], organized by [[Ivan Mijakovic]], Christophe Grangeasse, Alan Kent Nielsen and [[Jörg Stülke]] will take place from September 09 to 10 in Göttingen, Germany. [[PTM meeting 2014|website]], [http://subtiwiki.uni-goettingen.de/data/Registration_form_PTM_2014 Registration form], [mailto:jstuelk@gwdg.de contact]
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<big>'''Paper of the month: April 2014'''</big>  
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<big>'''Paper of the month: May 2014'''</big>  
* [[DNA repair/ recombination|DNA repair and recombination]] involve the unwinding and digestion of the DNA duplex by the [[AddA]]-[[AddB]] complex from the broken end until they encounter a χ sequence, whereupon the proteins produce a 3′ single-stranded DNA tail onto which they initiate loading of the [[RecA]] protein. Now, two studies from the lab of [[Mark Dillingham]] address the structure of [[AddA]]-[[AddB]] complexed to a χ sequence, and the effect of χ binding for processivity and ATP hydrolysis by [[AddA]]-[[AddB]].
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* The knowledge about absolute numbers of molecules of a given protein is often important, e. g. in the context of systems biology or to evaluate the relevance of experimentally observed [[protein-protein interactions]]. [http://www.ncbi.nlm.nih.gov/pubmed/24696501 Muntel et al.] from the lab of [[Dörte Becher]] have now determined absolute protein concentrations for about 1,000 cytosolic proteins. The results of this study have been added to the SubtiWiki gene pages (see # Expression and regulation). In this study, [[hag|flagellin]] was found to be the most abundant protein of ''B. subtilis''.
* '''Relevant ''Subti''Wiki pages:''' [[Mark Dillingham]], [[DNA repair/ recombination]], [[AddA]], [[AddB]]
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* '''Relevant ''Subti''Wiki pages:''' [[Dörte Becher]], [[Michael Hecker]], [[Vincent Fromion]], [[Ulrike Mäder]], [[genome-wide analyses]], [[protein-protein interactions]]
<pubmed> 24682829 24670664 </pubmed>
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<pubmed> 24696501 </pubmed>
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* [[Previous papers of the month]]
 
* [[Previous papers of the month]]
  

Revision as of 16:34, 9 May 2014

Welcome to SubtiWiki! - Bacillus subtilis annotation the "wiki" way!

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Contact: General Microbiology, University of Göttingen, send mail


Upcoming events:


New: Subtiwiki is now on Facebook - please give it a +1!



Now online: A new description of SubtiWiki and its acompanying modules in the 2014 Database issue of Nucleic Acids Research

Raphael H Michna, Fabian M Commichau, Dominik Tödter, Christopher P Zschiedrich, Jörg Stülke
SubtiWiki-a database for the model organism Bacillus subtilis that links pathway, interaction and expression information.
Nucleic Acids Res: 2014, 42(Database issue);D692-8
[PubMed:24178028] [WorldCat.org] [DOI] (I p)



Paper of the month: May 2014

Jan Muntel, Vincent Fromion, Anne Goelzer, Sandra Maaβ, Ulrike Mäder, Knut Büttner, Michael Hecker, Dörte Becher
Comprehensive absolute quantification of the cytosolic proteome of Bacillus subtilis by data independent, parallel fragmentation in liquid chromatography/mass spectrometry (LC/MS(E)).
Mol Cell Proteomics: 2014, 13(4);1008-19
[PubMed:24696501] [WorldCat.org] [DOI] (I p)



New procedure for account creation:

  • Due to massive spam attacks, we had to change our policy for the creation of accounts. If you want to create an account, just send me a mail. We will create the account for you as quickly as possible, then you can change your password. This does not affect existing accounts, which remain active.
  • Please remember that all members of the Bacillus community are invited to create accounts and to contribute to SubtiWiki!



News in SubtiWiki:

  • April 2013: SubtiWiki uses a new, faster Mediawiki platform! The times for page access are significantly reduced. Enjoy!
  • March 2013: updated Excel files that map all genes to categories and regulons as well as the general updated identity mapping of all genes were uploaded.
  • October 2012: the essential genes have been categorized
  • September 2012: 300 mutant strains available at the BGSC were added to the corresponding gene pages
  • August 2012: SubtiExpress, the new compagnon of SubtiWiki devoted to gene expression is online! Try it out!
  • April 2012: Links for expression data under 104 different conditions (based on Nicolas et al., 2012) have been added to the expression section of the individual gene pages
  • April 2011: SubtInteract, a presentation of protein-protein interactions in B. subtilis, is online!
  • December 2010: SubtiCellPublisher allows the conversion of CellDesigner diagrams to navigatable presentations in the style of SubtiPathways



Genes (examples) Additional pages
spo0A SubtiPathways
glnA SubtInteract
rny SubtiExpress
psdA Regulons
pckA methods
dnaA metabolism
rnpA categories
sigB genome-wide analyses
ptkA list of plasmids
mreC labs working on Bacillus
ccpA the people behind SubtiWiki
sr1 template


Publications describing SubtiWiki and SubtiPathways:

Raphael H Michna, Fabian M Commichau, Dominik Tödter, Christopher P Zschiedrich, Jörg Stülke
SubtiWiki-a database for the model organism Bacillus subtilis that links pathway, interaction and expression information.
Nucleic Acids Res: 2014, 42(Database issue);D692-8
[PubMed:24178028] [WorldCat.org] [DOI] (I p)

Ulrike Mäder, Arne G Schmeisky, Lope A Flórez, Jörg Stülke
SubtiWiki--a comprehensive community resource for the model organism Bacillus subtilis.
Nucleic Acids Res: 2012, 40(Database issue);D1278-87
[PubMed:22096228] [WorldCat.org] [DOI] (I p)

Lope A Flórez, Sebastian F Roppel, Arne G Schmeisky, Christoph R Lammers, Jörg Stülke
A community-curated consensual annotation that is continuously updated: the Bacillus subtilis centred wiki SubtiWiki.
Database (Oxford): 2009, 2009;bap012
[PubMed:20157485] [WorldCat.org] [DOI] (I p)

Christoph R Lammers, Lope A Flórez, Arne G Schmeisky, Sebastian F Roppel, Ulrike Mäder, Leendert Hamoen, Jörg Stülke
Connecting parts with processes: SubtiWiki and SubtiPathways integrate gene and pathway annotation for Bacillus subtilis.
Microbiology (Reading): 2010, 156(Pt 3);849-859
[PubMed:19959575] [WorldCat.org] [DOI] (I p)