Difference between revisions of "MaeN"

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* '''Operon:'''  
 
* '''Operon:'''  
  
* '''Sigma factor:'''  
+
* '''[[Sigma factor]]:'''  
  
 
* '''Regulation:''' induced by malate ([[MalR]])
 
* '''Regulation:''' induced by malate ([[MalR]])

Revision as of 09:21, 8 April 2009

  • Description: Na+/malate symporter

Gene name maeN
Synonyms yufR
Essential no
Product Na+/malate symporter
Function malate uptake
MW, pI 47 kDa, 8.411
Gene length, protein length 1344 bp, 448 aa
Immediate neighbours yufQ, yufS
Gene sequence (+200bp) Protein sequence
Genetic context
MaeN context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: 2-hydroxycarboxylate transporter family
  • Paralogous protein(s): CimH

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • Swiss prot entry:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation: induced by malate (MalR)
  • Regulatory mechanism: MalR: transcription activation
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Tanaka, K., K. Kobayashi, and N. Ogasawara. 2003. The Bacillus subtilis YufLM two-component system regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Microbiology 149: 2317-2329. PubMed
  2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed