LytG

• Description: similar to N-acetylmuramoyl-L-alanine amidase
  
  

Gene name	lytG
Synonyms	yubE
Essential	no
Product	unknown
Function	cell wall turnover
MW, pI	31 kDa, 8.277
Gene length, protein length	846 bp, 282 aa
Immediate neighbours	yubF, yubD
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU31120

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Hydrolysis of 1,4-beta-linkages between N-acetyl-D-glucosamine and N-acetylmuramic acid residues in a peptidoglycan (according to Swiss-Prot)

• Protein family: glycosyl hydrolase 73 family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: secreted (according to Swiss-Prot)

Database entries

• Structure:

• Swiss prot entry: O32083

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Fusinita van den Ent, Mark Leaver, Felipe Bendezu, Jeff Errington, Piet de Boer, Jan Löwe
Dimeric structure of the cell shape protein MreC and its functional implications.
Mol Microbiol: 2006, 62(6);1631-42
[PubMed:17427287] [WorldCat.org] [DOI] (P p)

Gavin J Horsburgh, Abdelmadjid Atrih, Michael P Williamson, Simon J Foster
LytG of Bacillus subtilis is a novel peptidoglycan hydrolase: the major active glucosaminidase.
Biochemistry: 2003, 42(2);257-64
[PubMed:12525152] [WorldCat.org] [DOI] (P p)

1. Horsburgh GJ, Atrih A, Williamson MP, Foster SJ. (2006) Dimeric structure of the cell shape protein MreC and its functional implications. Mol Microbiol. Dec;62(6): 1631-42. PubMed
2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed