Difference between revisions of "LytA"

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(Expression and regulation)
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=Expression and regulation=
 
=Expression and regulation=
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* '''Operon:''' ''[[lytA]]-[[lytB]]-[[lytC]]'' {{PubMed|1357079}}
  
* '''Operon:''' ''[[lytA]]-[[lytB]]-[[lytC]]''
+
* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|1357079}}, [[SigD]] {{PubMed|1357079}}
 
 
* '''[[Sigma factor]]:''' [[SigA]], [[SigD]]
 
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
  
* '''Regulatory mechanism:''' repressed by [[YvrHb]]  [http://www.ncbi.nlm.nih.gov/sites/entrez/16306698 PubMed]
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* '''Regulatory mechanism:'''  
 +
** [[LytR]]: transcription repression {{PubMed|1357079,16306698}}
 +
** [[YvrHb]]: transcription repression {{PubMed|16306698}}
  
 
* '''Additional information:'''
 
* '''Additional information:'''

Revision as of 21:00, 4 January 2010

  • Description: secretion of major autolysin LytC

Gene name lytA
Synonyms lppX
Essential no
Product secretion of major autolysin LytC
Function autolysis
MW, pI 11 kDa, 4.061
Gene length, protein length 306 bp, 102 aa
Immediate neighbours lytB, lytR
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
LytA context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU35640

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Masakuni Serizawa, Keisuke Kodama, Hiroki Yamamoto, Kazuo Kobayashi, Naotake Ogasawara, Junichi Sekiguchi
Functional analysis of the YvrGHb two-component system of Bacillus subtilis: identification of the regulated genes by DNA microarray and northern blot analyses.
Biosci Biotechnol Biochem: 2005, 69(11);2155-69
[PubMed:16306698] [WorldCat.org] [DOI] (P p)

V Lazarevic, P Margot, B Soldo, D Karamata
Sequencing and analysis of the Bacillus subtilis lytRABC divergon: a regulatory unit encompassing the structural genes of the N-acetylmuramoyl-L-alanine amidase and its modifier.
J Gen Microbiol: 1992, 138(9);1949-61
[PubMed:1357079] [WorldCat.org] [DOI] (P p)