Difference between revisions of "LutR"

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(Labs working on this gene/protein)
(Biological materials)
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=Biological materials =
 
=Biological materials =
  
* '''Mutant:'''
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* '''Mutant:''' [[lutR::Tn10::spc]]
  
 
* '''Expression vector:'''
 
* '''Expression vector:'''

Revision as of 10:38, 8 November 2013

Gene name lutR
Synonyms yvfI
Essential no
Product transcriptional repressor, (GntR family)
Function control of lactate utilization
Gene expression levels in SubtiExpress: lutR
Metabolic function and regulation of this protein in SubtiPathways:
Central C-metabolism
MW, pI 19 kDa, 4.845
Gene length, protein length 525 bp, 175 aa
Immediate neighbours lacR, lutP
Sequences Protein DNA DNA_with_flanks
Genetic context
YvfI context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
LutR expression.png




























Categories containing this gene/protein

utilization of specific carbon sources, transcription factors and their control

This gene is a member of the following regulons

The LutR regulon:

The gene

Basic information

  • Locus tag: BSU34180

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: transcriptional repressor of the lutA-lutB-lutC operon PubMed
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity: lactate acts as molecular inducer PubMed

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Richard Losick, Harvard Univ., Cambridge, USA homepage

Ayten Katatas, Istanbul Technical University, Istanbul, Turkey [3]

Your additional remarks

References

Öykü İrigül-Sönmez, Türkan E Köroğlu, Büşra Öztürk, Ákos T Kovács, Oscar P Kuipers, Ayten Yazgan-Karataş
In Bacillus subtilis LutR is part of the global complex regulatory network governing the adaptation to the transition from exponential growth to stationary phase.
Microbiology (Reading): 2014, 160(Pt 2);243-260
[PubMed:24196425] [WorldCat.org] [DOI] (I p)

Yunrong Chai, Roberto Kolter, Richard Losick
A widely conserved gene cluster required for lactate utilization in Bacillus subtilis and its involvement in biofilm formation.
J Bacteriol: 2009, 191(8);2423-30
[PubMed:19201793] [WorldCat.org] [DOI] (I p)

Additional publications: PubMed