Difference between revisions of "LutP"

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= [[Categories]] containing this gene/protein =
 
= [[Categories]] containing this gene/protein =
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yvfH_3510780_3512471_1 lutP] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yvfH_3510780_3512471_1 lutP] {{PubMed|22383849}}
  
* '''Sigma factor:'''  
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* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|25031425}}
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
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=References=
 
=References=
  
<pubmed> 19201793, 18763711 16091051</pubmed>
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<pubmed> 19201793, 18763711 16091051 25031425 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 08:29, 18 July 2014

  • Description: lactate permease

Gene name lutP
Synonyms yvfH
Essential no
Product lactate permease
Function lactate uptake
Gene expression levels in SubtiExpress: lutP
Metabolic function and regulation of this protein in SubtiPathways:
lutP
MW, pI 59 kDa, 9.476
Gene length, protein length 1689 bp, 563 aa
Immediate neighbours lutR, sigL
Sequences Protein DNA DNA_with_flanks
Genetic context
YvfH context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
500px















Categories containing this gene/protein

transporters/ other, utilization of specific carbon sources, membrane proteins

This gene is a member of the following regulons

ComA regulon

The gene

Basic information

  • Locus tag: BSU34190

Phenotypes of a mutant

poor growth with lactate as single carbon source PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: lactate uptake PubMed
  • Protein family: lactate permease family (according to Swiss-Prot)
  • Paralogous protein(s): LctP

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Additional information:
    • number of protein molecules per cell (complex medium with amino acids, without glucose): 743 PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Richard Losick, Harvard Univ., Cambridge, USA homepage

Your additional remarks

References

Kuo-Chin Chiu, Chen-Jyun Lin, Gwo-Chyuan Shaw
Transcriptional regulation of the l-lactate permease gene lutP by the LutR repressor of Bacillus subtilis RO-NN-1.
Microbiology (Reading): 2014, 160(Pt 10);2178-2189
[PubMed:25031425] [WorldCat.org] [DOI] (I p)

Yunrong Chai, Roberto Kolter, Richard Losick
A widely conserved gene cluster required for lactate utilization in Bacillus subtilis and its involvement in biofilm formation.
J Bacteriol: 2009, 191(8);2423-30
[PubMed:19201793] [WorldCat.org] [DOI] (I p)

Hannes Hahne, Susanne Wolff, Michael Hecker, Dörte Becher
From complementarity to comprehensiveness--targeting the membrane proteome of growing Bacillus subtilis by divergent approaches.
Proteomics: 2008, 8(19);4123-36
[PubMed:18763711] [WorldCat.org] [DOI] (I p)

Natalia Comella, Alan D Grossman
Conservation of genes and processes controlled by the quorum response in bacteria: characterization of genes controlled by the quorum-sensing transcription factor ComA in Bacillus subtilis.
Mol Microbiol: 2005, 57(4);1159-74
[PubMed:16091051] [WorldCat.org] [DOI] (P p)