Difference between revisions of "LutC"

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=== Basic information/ Evolution ===
 
=== Basic information/ Evolution ===
  
* '''Catalyzed reaction/ biological activity:'''  
+
* '''Catalyzed reaction/ biological activity:''' oxidation of lactate to pyruvate
  
 
* '''Protein family:'''
 
* '''Protein family:'''
Line 88: Line 88:
 
=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:'''  
+
* '''Operon:''' ''[[lutA]]-[[lutB]]-[[lutC]]''
  
 
* '''Sigma factor:'''  
 
* '''Sigma factor:'''  
  
* '''Regulation:'''  
+
* '''Regulation:''' induction by lactate
  
* '''Regulatory mechanism:'''  
+
* '''Regulatory mechanism:''' dual repression by [[LutR]] (inducer lactate) and [[SinR]]
  
 
* '''Additional information:'''  
 
* '''Additional information:'''  
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=Labs working on this gene/protein=
 
=Labs working on this gene/protein=
 +
 +
[[Richard Losick]], Harvard Univ., Cambridge, USA [http://www.mcb.harvard.edu/Losick/ homepage]
  
 
=Your additional remarks=
 
=Your additional remarks=

Revision as of 14:22, 7 February 2009

  • Description: lactate catabolic enzyme

Gene name lutC
Synonyms yvbY
Essential
Product
Function utilization of lactate
MW, pI 26 kDa, 5.157
Gene length, protein length 720 bp, 240 aa
Immediate neighbours
Gene sequence (+200bp) Protein sequence
Genetic context
YvbY context.gif



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: oxidation of lactate to pyruvate
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • Swiss prot entry:
  • KEGG entry:
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation: induction by lactate
  • Regulatory mechanism: dual repression by LutR (inducer lactate) and SinR
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Richard Losick, Harvard Univ., Cambridge, USA homepage

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed