Difference between revisions of "LutA"
| Line 39: | Line 39: | ||
===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
| − | no growth with lactate as the single carbon source | + | no growth with lactate as the single carbon source [http://www.ncbi.nlm.nih.gov/sites/entrez/19201793 PubMed] |
=== Database entries === | === Database entries === | ||
| Line 54: | Line 54: | ||
=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' oxidation of lactate to pyruvate | + | * '''Catalyzed reaction/ biological activity:''' oxidation of lactate to pyruvate [http://www.ncbi.nlm.nih.gov/sites/entrez/19201793 PubMed] |
* '''Protein family:''' | * '''Protein family:''' | ||
| Line 90: | Line 90: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' ''[[lutA]]-[[lutB]]-[[lutC]]'' | + | * '''Operon:''' ''[[lutA]]-[[lutB]]-[[lutC]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/19201793 PubMed] |
* '''Sigma factor:''' | * '''Sigma factor:''' | ||
| − | * '''Regulation:''' induction by lactate | + | * '''Regulation:''' induction by lactate [http://www.ncbi.nlm.nih.gov/sites/entrez/19201793 PubMed] |
| − | * '''Regulatory mechanism:''' dual repression by [[LutR]] (inducer lactate) and [[SinR]] | + | * '''Regulatory mechanism:''' dual repression by [[LutR]] (inducer lactate) and [[SinR]] [http://www.ncbi.nlm.nih.gov/sites/entrez/19201793 PubMed] |
* '''Additional information:''' | * '''Additional information:''' | ||
Revision as of 16:45, 10 February 2009
- Description: lactate catabolic enzyme
| Gene name | lutA |
| Synonyms | yvfV |
| Essential | |
| Product | |
| Function | lactate utilization |
| MW, pI | 26 kDa, 6.25 |
| Gene length, protein length | 714 bp, 238 aa |
| Immediate neighbours | |
| Gene sequence (+200bp) | Protein sequence |
Genetic context 
| |
Contents
The gene
Basic information
- Coordinates:
Phenotypes of a mutant
no growth with lactate as the single carbon source PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: oxidation of lactate to pyruvate PubMed
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- Swiss prot entry:
- KEGG entry:
- E.C. number:
Additional information
Expression and regulation
- Sigma factor:
- Regulation: induction by lactate PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Richard Losick, Harvard Univ., Cambridge, USA homepage
Your additional remarks
References
- Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed
