Difference between revisions of "LrpC"

From SubtiWiki
Jump to: navigation, search
(References)
Line 1: Line 1:
* '''Description:''' transcription regulator <br/><br/>
+
* '''Description:''' sequence-independent DNA-binding and DNA-bending protein, facilitates the formation of higher order protein-DNA complexes <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
Line 10: Line 10:
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || transcription regulator
+
|style="background:#ABCDEF;" align="center"| '''Product''' || DNA-binding and -bending protein
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
+
|style="background:#ABCDEF;" align="center"|'''Function''' || DNA repair and recombination
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 16 kDa, 7.743   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 16 kDa, 7.743   

Revision as of 15:36, 1 February 2010

  • Description: sequence-independent DNA-binding and DNA-bending protein, facilitates the formation of higher order protein-DNA complexes

Gene name lrpC
Synonyms ydaI
Essential no
Product DNA-binding and -bending protein
Function DNA repair and recombination
MW, pI 16 kDa, 7.743
Gene length, protein length 432 bp, 144 aa
Immediate neighbours ydzA, topB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
LrpC context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU04250

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information: 50 ... 300 molecules per cell PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Gema López-Torrejón, María I Martínez-Jiménez, Silvia Ayora
Role of LrpC from Bacillus subtilis in DNA transactions during DNA repair and recombination.
Nucleic Acids Res: 2006, 34(1);120-9
[PubMed:16407330] [WorldCat.org] [DOI] (I e)

Christophe Beloin, Josette Jeusset, Bernard Revet, Gilles Mirambeau, Francoise Le Hégarat, Eric Le Cam
Contribution of DNA conformation and topology in right-handed DNA wrapping by the Bacillus subtilis LrpC protein.
J Biol Chem: 2003, 278(7);5333-42
[PubMed:12458218] [WorldCat.org] [DOI] (P p)

C Beloin, R Exley, A L Mahé, M Zouine, S Cubasch, F Le Hégarat
Characterization of LrpC DNA-binding properties and regulation of Bacillus subtilis lrpC gene expression.
J Bacteriol: 2000, 182(16);4414-24
[PubMed:10913073] [WorldCat.org] [DOI] (P p)

A Tapias, G López, S Ayora
Bacillus subtilis LrpC is a sequence-independent DNA-binding and DNA-bending protein which bridges DNA.
Nucleic Acids Res: 2000, 28(2);552-9
[PubMed:10606655] [WorldCat.org] [DOI] (I p)

C Beloin, S Ayora, R Exley, L Hirschbein, N Ogasawara, Y Kasahara, J C Alonso, F L Hégarat
Characterization of an lrp-like (lrpC) gene from Bacillus subtilis.
Mol Gen Genet: 1997, 256(1);63-71
[PubMed:9341680] [WorldCat.org] [DOI] (P p)