LplD

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  • Description: α-galacturonidase

Gene name lplD
Synonyms
Essential no
Product α-galacturonidase
Function utilization of pectin
Gene expression levels in SubtiExpress: lplD
MW, pI 49 kDa, 5.356
Gene length, protein length 1338 bp, 446 aa
Immediate neighbours lplC, yetF
Sequences Protein DNA DNA_with_flanks
Genetic context
LplD context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
LplD expression.png















Categories containing this gene/protein

poorly characterized/ putative enzymes, sporulation proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU07130

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • cleavage of α-1,4-di-galacturonate PubMed
  • Protein family: glycosyl hydrolase 4 family PubMed
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
    • active site motif: CHEV PubMed
  • Modification:
  • Cofactor(s): NAD, Mn(2+) PubMed
  • Effectors of protein activity:

Database entries

  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

John Thompson, Andreas Pikis, Jamie Rich, Barry G Hall, Stephen G Withers
α-Galacturonidase(s): a new class of Family 4 glycoside hydrolases with strict specificity and a unique CHEV active site motif.
FEBS Lett: 2013, 587(6);799-803
[PubMed:23416295] [WorldCat.org] [DOI] (I p)