Difference between revisions of "LplD"
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| − | * '''Description:''' | + | * '''Description:''' α-galacturonidase <br/><br/> |
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
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| − | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || α-galacturonidase |
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| − | |style="background:#ABCDEF;" align="center"|'''Function''' || | + | |style="background:#ABCDEF;" align="center"|'''Function''' || utilization of pectin |
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU07130 lplD] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU07130 lplD] | ||
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<br/><br/><br/><br/> | <br/><br/><br/><br/> | ||
<br/><br/><br/><br/> | <br/><br/><br/><br/> | ||
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* '''Catalyzed reaction/ biological activity:''' | * '''Catalyzed reaction/ biological activity:''' | ||
| + | ** cleavage of α-1,4-di-galacturonate {{PubMed|23416295}} | ||
| − | * '''Protein family:''' glycosyl hydrolase 4 family | + | * '''Protein family:''' glycosyl hydrolase 4 family {{PubMed|23416295}} |
* '''Paralogous protein(s):''' | * '''Paralogous protein(s):''' | ||
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* '''Domains:''' | * '''Domains:''' | ||
| + | ** active site motif: CHEV {{PubMed|23416295}} | ||
* '''Modification:''' | * '''Modification:''' | ||
| − | * '''Cofactor(s):''' | + | * '''Cofactor(s):''' NAD, Mn(2+) {{PubMed|23416295}} |
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
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=References= | =References= | ||
| − | + | <pubmed> 23416295 </pubmed> | |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 16:25, 16 August 2013
- Description: α-galacturonidase
| Gene name | lplD |
| Synonyms | |
| Essential | no |
| Product | α-galacturonidase |
| Function | utilization of pectin |
| Gene expression levels in SubtiExpress: lplD | |
| MW, pI | 49 kDa, 5.356 |
| Gene length, protein length | 1338 bp, 446 aa |
| Immediate neighbours | lplC, yetF |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
poorly characterized/ putative enzymes, sporulation proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU07130
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- cleavage of α-1,4-di-galacturonate PubMed
- Protein family: glycosyl hydrolase 4 family PubMed
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- active site motif: CHEV PubMed
- Modification:
- Cofactor(s): NAD, Mn(2+) PubMed
- Effectors of protein activity:
Database entries
- Structure: 3FEF
- UniProt: P39130
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
John Thompson, Andreas Pikis, Jamie Rich, Barry G Hall, Stephen G Withers
α-Galacturonidase(s): a new class of Family 4 glycoside hydrolases with strict specificity and a unique CHEV active site motif.
FEBS Lett: 2013, 587(6);799-803
[PubMed:23416295]
[WorldCat.org]
[DOI]
(I p)
