licR

168

transcriptional activator of the [gene|65FC7F4ED92F747DB7BC5672DCA2D2320A471134|licB]-[gene|83A7C160B0301A2B51B65478D99ACB753D67AF74|licC]-[gene|E8B6C8E722BEE866878CDD816B7828C132F94FCD|licA]-[gene|84D8AA0AFBF46273F6B4198B49440D55470FEC0F|licH] operon

locus: BSU_38600

Molecular weight: 73.14 kDa

pI: 6.11

Protein length: 641 aa

Gene length: 1926 bp

function: regulation of lichenan utilization

product: transcriptional activator, [wiki|PRD]-type

essential: no

ec: 2.7.1.69

synonyms: licR, celR

List of homologs in different organisms, belongs to COG3711 (Galperin et al., 2021)

Gene

Coordinates: 3,962,003 → 3,963,928

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The protein

Protein family

• [wiki|PRD-containing transcription factors]

[wiki|Domains]

• 2 [wiki|PRD] domains (aa 184-289, aa 296-403)
• [wiki|PTS EIIB domain] type-2 (aa 407-498)
• [wiki|PTS EIIA domain] type-2 (aa 499-638)

Structure

• [AF|P46321]

Modification

• phosphorylation (His219, His278, His333, His392, Cys413, His559) (according to Swiss-Prot)

Expression and Regulation

Operons

• genes: [gene|E087ABA705CE94E2CAD44A0F2FB265B0F7B04399|licR]

  description: [Pubmed|8990303]

  sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|8990303], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]

Biological materials

Mutant

• BKE38600 (Δ[gene|E087ABA705CE94E2CAD44A0F2FB265B0F7B04399|licR]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE38600 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGAGAAAAACCTCCTAAC,  downstream forward: _UP4_TGACAGCCTGTATATACCTT
• BKK38600 (Δ[gene|E087ABA705CE94E2CAD44A0F2FB265B0F7B04399|licR]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK38600 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGAGAAAAACCTCCTAAC,  downstream forward: _UP4_TGACAGCCTGTATATACCTT

References

• 8990303,10438772