LiaR

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Gene name liaR
Synonyms yvqC
Essential no
Product two-component response regulator
Function regulation of the liaI-liaH-liaG-liaF-liaS-liaR

operon in response to bacitracin

Interactions involving this protein in SubtInteract: LiaR
MW, pI 22 kDa, 4.956
Gene length, protein length 633 bp, 211 aa
Immediate neighbours gerAC, liaS
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YvqC context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

transcription factors and their control, resistance against oxidative and electrophile stress, resistance against toxins/ antibiotics, phosphoproteins

This gene is a member of the following regulons

LiaR regulon

The LiaR regulon

The gene

Basic information

  • Locus tag: BSU33080

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: regulation of the liaI-liaH-liaG-liaF-liaS-liaR operon in response to bacitracin
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification: phosphorylation on a Asp residue by LiaS
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

John Helmann, Cornell University, USA Homepage


Your additional remarks

References

Additional publications: PubMed