LdcB

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  • Description: LD-carboxypeptidase

Gene name ldcB
Synonyms yodJ
Essential no
Product LD-carboxypeptidase
Function cell wall synthesis
Gene expression levels in SubtiExpress: yodJ
MW, pI 30 kDa, 5.84
Gene length, protein length 819 bp, 273 aa
Immediate neighbours yodI, deoD
Sequences Protein DNA DNA_with_flanks
Genetic context
YodJ context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YodJ expression.png















Categories containing this gene/protein

cell wall synthesis

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU19620

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • trimming of cell wall peptides (tetrapeptides to tripeptides) PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Christopher N Hoyland, Christine Aldridge, Robert M Cleverley, Marie-Clémence Duchêne, George Minasov, Olena Onopriyenko, Karzan Sidiq, Peter J Stogios, Wayne F Anderson, Richard A Daniel, Alexei Savchenko, Waldemar Vollmer, Richard J Lewis
Structure of the LdcB LD-carboxypeptidase reveals the molecular basis of peptidoglycan recognition.
Structure: 2014, 22(7);949-60
[PubMed:24909784] [WorldCat.org] [DOI] (I p)

Birgit Voigt, Haike Antelmann, Dirk Albrecht, Armin Ehrenreich, Karl-Heinz Maurer, Stefan Evers, Gerhard Gottschalk, Jan Maarten van Dijl, Thomas Schweder, Michael Hecker
Cell physiology and protein secretion of Bacillus licheniformis compared to Bacillus subtilis.
J Mol Microbiol Biotechnol: 2009, 16(1-2);53-68
[PubMed:18957862] [WorldCat.org] [DOI] (I p)