Difference between revisions of "LctP"

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(Expression and regulation)
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* '''[[Sigma factor]]:'''  
 
* '''[[Sigma factor]]:'''  
  
* '''Regulation:''' induced under anaerobic conditions ([[Rex]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/16207915 PubMed]
+
* '''Regulation:'''  
** repressed at regular oxygen concentration ([[Rex]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/16207915 PubMed]
+
** induced under anaerobic conditions ([[Rex]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/16207915 PubMed]
  
* '''Regulatory mechanism:''' [[Rex]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/16207915 PubMed]
+
* '''Regulatory mechanism:'''  
** [[Rex]]: transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/16207915 PubMed]
+
** [[Rex]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/16207915 PubMed]
  
 
* '''Additional information:'''
 
* '''Additional information:'''

Revision as of 05:07, 12 June 2009

  • Description: lactate permease, excretion

Gene name lctP
Synonyms ycgC
Essential no
Product L-lactate permease
Function lactate excretion
Metabolic function and regulation of this protein in SubtiPathways:
Central C-metabolism
MW, pI 57 kDa, 9.766
Gene length, protein length 1623 bp, 541 aa
Immediate neighbours ldh, mdr
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
LctP context.gif
This image was kindly provided by SubtiList





The gene

Basic information

  • Locus tag: BSU03060

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: lactate permease family (according to Swiss-Prot)
  • Paralogous protein(s): LutP

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • induced under anaerobic conditions (Rex) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed