KtrD

• Description: low affinity potassium transporter KtrC-KtrD, integral membrane subunit
  
  

Gene name	ktrD
Synonyms	ykrM
Essential	no
Product	low affinity potassium transporter KtrC-KtrD, integral membrane subunit (proton symport)
Function	potassium uptake
Metabolic function and regulation of this protein in SubtiPathways: Stress
MW, pI	49 kDa, 9.224
Gene length, protein length	1347 bp, 449 aa
Immediate neighbours	ykrL, ykzE
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU13500

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

Categories containing this gene/protein

transporters/ other, metal ion homeostasis (K, Na, Ca, Mg), coping with hyper-osmotic stress, membrane proteins

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: View classification (according to Swiss-Prot)

• Paralogous protein(s): KtrB

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: KtrC-KtrD PubMed

• Localization: cell membrane (according to Swiss-Prot), integral membrane protein PubMed

Database entries

• Structure:

• UniProt: O31658

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: ktrD PubMed

• Sigma factor:

• Regulation: constitutively expressed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Erhard Bremer, University of Marburg, Germany homepage

References

Gudrun Holtmann, Evert P Bakker, Nobuyuki Uozumi, Erhard Bremer
KtrAB and KtrCD: two K+ uptake systems in Bacillus subtilis and their role in adaptation to hypertonicity.
J Bacteriol: 2003, 185(4);1289-98
[PubMed:12562800] [WorldCat.org] [DOI] (P p)