KinE

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Gene name kinE
Synonyms ykrQ
Essential no
Product two-component sensor kinase
Function initiation of sporulation
Interactions involving this protein in SubtInteract: KinE
Function and regulation of this protein in SubtiPathways:
Phosphorelay
MW, pI 85 kDa, 5.489
Gene length, protein length 2214 bp, 738 aa
Immediate neighbours ykrP, ogt
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
KinE context.gif
This image was kindly provided by SubtiList







Categories containing this gene/protein

protein modification, transcription factors and their control, phosphorelay, membrane proteins, phosphoproteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU13530

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: autophosphorylation, phosphorylation of Spo0F
  • Protein family:

Extended information on the protein

  • Kinetic information:
  • Domains: two transmembrane segments, C-terminal histidine phosphotransferase domain
  • Modification: autophosphorylation on a His residue
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

M Jiang, W Shao, M Perego, J A Hoch
Multiple histidine kinases regulate entry into stationary phase and sporulation in Bacillus subtilis.
Mol Microbiol: 2000, 38(3);535-42
[PubMed:11069677] [WorldCat.org] [DOI] (P p)

C Fabret, V A Feher, J A Hoch
Two-component signal transduction in Bacillus subtilis: how one organism sees its world.
J Bacteriol: 1999, 181(7);1975-83
[PubMed:10094672] [WorldCat.org] [DOI] (P p)

F Morohoshi, K Hayashi, N Munakata
Bacillus subtilis gene coding for constitutive O6-methylguanine-DNA alkyltransferase.
Nucleic Acids Res: 1989, 17(16);6531-43
[PubMed:2506524] [WorldCat.org] [DOI] (P p)