Difference between revisions of "KinC"
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| − | * '''Description:''' [[two-component systems|two-component]] sensor kinase, phosphorylates [[Spo0F]], part of the [[phosphorelay]] <br/><br/> | + | * '''Description:''' [[two-component systems|two-component]] sensor kinase, phosphorylates [[Spo0F]] and [[Spo0A]], part of the [[phosphorelay]] <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
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=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' | + | * '''Catalyzed reaction/ biological activity:''' phosphorylation of [[Spo0F]] as part of the [[phosphorelay]], but also direct phosphorylation of [[Spo0A]] {{PubMed|19114652}} |
* '''Protein family:''' | * '''Protein family:''' | ||
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* '''Cofactor(s):''' | * '''Cofactor(s):''' | ||
| − | * '''Effectors of protein activity:''' | + | * '''Effectors of protein activity:''' activity is triggered by potassium leakage {{PubMed|19114652}} |
| − | * '''Interactions:''' | + | * '''Interactions:''' [[KinC]]-[[Spo0A]] {{PubMed|19114652}} |
* '''Localization:''' cell membrane (according to Swiss-Prot), Membrane (Heterogeneous) [http://www.ncbi.nlm.nih.gov/sites/entrez/16479537 PubMed] | * '''Localization:''' cell membrane (according to Swiss-Prot), Membrane (Heterogeneous) [http://www.ncbi.nlm.nih.gov/sites/entrez/16479537 PubMed] | ||
Revision as of 09:00, 30 November 2009
- Description: two-component sensor kinase, phosphorylates Spo0F and Spo0A, part of the phosphorelay
| Gene name | kinC |
| Synonyms | ssb |
| Essential | no |
| Product | two-component sensor kinase |
| Function | initiation of sporulation |
| MW, pI | 48 kDa, 6.225 |
| Gene length, protein length | 1284 bp, 428 aa |
| Immediate neighbours | abh, ykqA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU14490
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: phosphorylation of Spo0F as part of the phosphorelay, but also direct phosphorylation of Spo0A PubMed
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains: two transmembrane segments, C-terminal histidine phosphotransferase domain
- Modification:
- Cofactor(s):
- Effectors of protein activity: activity is triggered by potassium leakage PubMed
- Localization: cell membrane (according to Swiss-Prot), Membrane (Heterogeneous) PubMed
Database entries
- Structure:
- UniProt: P39764
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: kinC (according to DBTBS)
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
