KduD

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  • Description: 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase

Gene name kduD
Synonyms
Essential no
Product
Function utilization of galacturonic acid
Gene expression levels in SubtiExpress: kduD
MW, pI 27 kDa, 6.498
Gene length, protein length 762 bp, 254 aa
Immediate neighbours kduI, ypvA
Sequences Protein DNA DNA_with_flanks
Genetic context
KduD context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
KduD expression.png
























Categories containing this gene/protein

utilization of specific carbon sources

This gene is a member of the following regulons

CcpA regulon, KdgR regulon

The gene

Basic information

  • Locus tag: BSU22140

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 2-deoxy-D-gluconate + NAD+ = 3-dehydro-2-deoxy-D-gluconate + NADH (according to Swiss-Prot)
  • Protein family: phosphopentomutase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Jer-Sheng Lin, Gwo-Chyuan Shaw
Regulation of the kduID operon of Bacillus subtilis by the KdgR repressor and the ccpA gene: identification of two KdgR-binding sites within the kdgR-kduI intergenic region.
Microbiology (Reading): 2007, 153(Pt 3);701-710
[PubMed:17322190] [WorldCat.org] [DOI] (P p)