Difference between revisions of "KduD"

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(Expression and regulation)
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=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:'''  
+
* '''Operon:''' ''[[kduI]]-[[kduD]]'' {{PubMed|17322190}}
  
* '''[[Sigma factor]]:'''  
+
* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|17322190}}
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
 +
** induced by galacturonate ([[KdgR]]) {{PubMed|17322190}}
 +
** repressed by glucose ([[CcpA]]) {{PubMed|17322190}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 +
** [[KdgR]]: transcription repression {{PubMed|17322190}}
 +
** [[CcpA]]: transcription repression {{PubMed|17322190}}
  
* '''Additional information:'''  
+
* '''Additional information:'''
  
 
=Biological materials =
 
=Biological materials =

Revision as of 20:34, 26 October 2009

  • Description: 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase

Gene name kduD
Synonyms
Essential no
Product
Function utilization of galacturonic acid
MW, pI 27 kDa, 6.498
Gene length, protein length 762 bp, 254 aa
Immediate neighbours kduI, ypvA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
KduD context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU22140

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 2-deoxy-D-gluconate + NAD+ = 3-dehydro-2-deoxy-D-gluconate + NADH (according to Swiss-Prot)
  • Protein family: phosphopentomutase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Jer-Sheng Lin, Gwo-Chyuan Shaw
Regulation of the kduID operon of Bacillus subtilis by the KdgR repressor and the ccpA gene: identification of two KdgR-binding sites within the kdgR-kduI intergenic region.
Microbiology (Reading): 2007, 153(Pt 3);701-710
[PubMed:17322190] [WorldCat.org] [DOI] (P p)