Difference between revisions of "Kbl"

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|style="background:#ABCDEF;" align="center"|'''Function''' || threonine utilization
 
|style="background:#ABCDEF;" align="center"|'''Function''' || threonine utilization
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU17000 kbl]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU17000 kbl]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/lys_threo.html Lys, Thr]'''
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/lys_threo.html Lys, Thr]'''
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[tdh]]'', ''[[ymcB]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[tdh]]'', ''[[ymcB]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB13573&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU17000 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU17000 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU17000 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:kbl_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:kbl_context.gif]]

Revision as of 12:53, 13 May 2013

  • Description: 2-amino-3-ketobutyrate CoA ligase

Gene name kbl
Synonyms
Essential no
Product 2-amino-3-ketobutyrate CoA ligase
Function threonine utilization
Gene expression levels in SubtiExpress: kbl
Metabolic function and regulation of this protein in SubtiPathways:
Lys, Thr
MW, pI 43 kDa, 6.25
Gene length, protein length 1176 bp, 392 aa
Immediate neighbours tdh, ymcB
Sequences Protein DNA Advanced_DNA
Genetic context
Kbl context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
Kbl expression.png



















Categories containing this gene/protein

utilization of amino acids

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU17000

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Acetyl-CoA + glycine = CoA + 2-amino-3-oxobutanoate (according to Swiss-Prot)
  • Protein family: class-II pyridoxal-phosphate-dependent aminotransferase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
    • pyridoxal-phosphate (according to Swiss-Prot)
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 1FC4 (from Escherichia coli, 40% identity, 60% similarity) PubMed
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References