IspF

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  • Description: 2-C-methyl-D-erythrol-2,4-cyclodiphosphate synthase

Gene name ispF
Synonyms yacN
Essential yes PubMed
Product 2-C-methyl-D-erythrol-2,4-cyclodiphosphate synthase
Function isoprenoid biosynthesis
MW, pI 16 kDa, 5.398
Gene length, protein length 474 bp, 158 aa
Immediate neighbours ispD, gltX
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YacN context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU00910

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol = 2-C-methyl-D-erythritol 2,4-cyclodiphosphate + CMP (according to Swiss-Prot)
  • Protein family: ispF family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References