IolE

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  • Description: 2-keto-myo-inositol dehydratase, dehydration of 2-keto-myo-inositol (2nd reaction)

Gene name iolE
Synonyms yxdE
Essential no
Product 2-keto-myo-inositol dehydratase,
dehydration of 2-keto-myo-inositol (2nd reaction)
Function myo-inositol catabolism
Metabolic function and regulation of this protein in SubtiPathways:
Sugar catabolism
MW, pI 33 kDa, 5.209
Gene length, protein length 891 bp, 297 aa
Immediate neighbours iolF, iolD
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
IolE context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU39720

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

Categories containing this gene/protein

utilization of specific carbon sources

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 2,4,6/3,5-pentahydroxycyclohexanone = 3,5/4-trihydroxycyclohexa-1,2-dione + H2O (according to Swiss-Prot)
  • Protein family: iolE/mocC family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure: 3CNY (from Lactobacillus plantarum wcfs1 mutant, 63% identity, 78% similarity)
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References