Difference between revisions of "IolA"

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=== Basic information ===
 
=== Basic information ===
  
* '''Locus tag:'''
+
* '''Locus tag:''' BSU39760
  
 
===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
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* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P42412 P42412]
 
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P42412 P42412]
  
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU39760 BSU39760]
+
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU39760]
  
 
* '''E.C. number:''' [http://www.expasy.org/enzyme/1.2.1.27 1.2.1.27]
 
* '''E.C. number:''' [http://www.expasy.org/enzyme/1.2.1.27 1.2.1.27]

Revision as of 11:43, 3 June 2009

  • Description: methylmalonate-semialdehyde dehydrogenase (acylating)

Gene name iolA
Synonyms mmsA, yxdA
Essential no
Product methylmalonate-semialdehyde dehydrogenase (acylating)
Function myo-inositol catabolism
MW, pI 53 kDa, 5.139
Gene length, protein length 1461 bp, 487 aa
Immediate neighbours iolB, iolR
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
MmsA context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU39760

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 3-oxopropanoate + CoA + NAD(P)+ = acetyl-CoA + CO2 + NAD(P)H (according to Swiss-Prot)
  • Protein family: IolA subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • KEGG entry: [3]

Additional information

Expression and regulation

  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Yoshida K, Yamaguchi M, Morinaga T, Kinehara M, Ikeuchi M, Ashida H, Fujita Y. (2008) myo-Inositol catabolism in Bacillus subtilis. J Biol Chem. Apr 18;283(16): 10415-24. PubMed